Two Guys Pizzeria

Pizza restaurant, Italian restaurant

Two Guys Pizzeria, located in Medical Center Plaza, is where pizza lovers can indulge in a delightful array of slices at unbeatable prices. Renowned for its quick service, this cozy spot offers diners both comfort and casual vibes, making it a favorite among locals and university students alike. Popular for lunch and dinner, the generous portions—a must-try being the Hawaiian pizza—are complemented by friendly, attentive staff. With outdoor seating and options for takeout or delivery, it’s a fantastic choice for families and groups seeking tasty comfort food.

Contact Info

  • Location: 2250 W Holcombe Blvd, Houston, TX 77030
  • Located in: Medical Center Plaza
  • Phone: (713) 660-6262
  • Price range: $
Two Guys Pizzeria

Opening hours

  • Monday: 11 am-9 pm
  • Tuesday: 11 am-10 pm
  • Wednesday: 11 am-10 pm
  • Thursday: 11 am-10 pm
  • Friday: 11 am-10 pm
  • Saturday: 11 am-10 pm
  • Sunday: 11 am-9 pm

Other Business Hours

Delivery

  • Monday: 11 am-8 pm
  • Tuesday: 11 am-9 pm
  • Wednesday: 11 am-9 pm
  • Thursday: 11 am-9 pm
  • Friday: 11 am-9 pm
  • Saturday: 11 am-9 pm
  • Sunday: 11 am-8 pm

Takeout

  • Monday: 11 am-8:30 pm
  • Tuesday: 11 am-9:30 pm
  • Wednesday: 11 am-9:30 pm
  • Thursday: 11 am-9:30 pm
  • Friday: 11 am-10:45 pm
  • Saturday: 11 am-10:45 pm
  • Sunday: 11 am-8:30 pm

Services

  • Wheelchair-accessible car park
  • Wheelchair-accessible entrance
  • Wheelchair-accessible seating
  • Wheelchair-accessible toilet
  • Outdoor seating
  • Kerbside pickup
  • No-contact delivery
  • Delivery
  • Takeaway
  • Dine-in
  • Fast service
  • Lunch
  • Dinner
  • Solo dining
  • Alcohol
  • Beer
  • Comfort food
  • Quick bite
  • Vegetarian options
  • Lunch
  • Dinner
  • Counter service
  • Dessert
  • Seating
  • Toilets
  • Casual
  • Cosy
  • Trendy
  • Groups
  • Tourists
  • University students
  • Accepts reservations
  • Credit cards
  • Debit cards
  • NFC mobile payments
  • Credit cards
  • Good for kids
  • Free parking lot
  • Plenty of parking
Two Guys Pizzeria Food & drink

Food & drink

Two Guys Pizzeria Vibe

Vibe

Two Guys Pizzeria Calzone

Calzone

Two Guys Pizzeria Pizza

Pizza

Two Guys Pizzeria Street View

Street View

Menus and Prices

Two Guys Pizzeria menu prices 1

Menu 1

Two Guys Pizzeria menu prices 2

Menu 2

Two Guys Pizzeria menu prices 3

Menu 3

Two Guys Pizzeria menu prices 4

Menu 4

Two Guys Pizzeria menu prices 5

Menu 5

Add Your Review

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Reviews

It’s a small crowded place.
The man behind the counter is extremely nice and explains everything so perfectly on the menu.
He seems like a genuine guy and the customer service is not forced.
The restaurant is pretty clean and I was very surprised when I use the restroom that it was also pretty clean.
I ordered two giant slices of pepperoni after he showed me a picture of what the slice size was.
When I got the two slices, they were far bigger than what he showed me, which I was definitely surprised.
The pizza is much better with their garlic seasoning that they have sitting on the table with it.
The pizza is actually pretty bland and the sauce is a tomato sauce with few seasoning.
Overall, the pizza was pretty decent.
I was glad that I ordered two slices, one of them was overcooked, and the other one was actually pretty good.


I love the atmosphere.
Pizza is fresh and flavor full.
Great to go with small groups.
Overall a really good family owned business


Let me do this again.
Last review was on my wrong profile.
This is delicious, I got my favorite Hawaiian pizza.
It’s better than little Ceasers, papa johns or dominos.
Idc what you like.
This is what I love.
Also I normally eat 1-2 slices, this time I hadn’t noticed that i ate more than that.
Like dude this is soooooo gooooddd.


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